The OraVital Microbiology Lab Biofilm Diagnostics

Do you have patients with periodontal disease, bad breath, or some other evident or potential symptoms of oral infection? Take a biofilm sample and send it to Biofilm Diagnostics. The detailed report you receive will accurately determine the extent of the infection and will be an invaluable guide for successful treatment. Our microbiologists are knowledgeable in both periodontal and caries pathogens.

Although there are several hundred species of bacteria present in the oral cavity, most of these are harmless and maintain a symbiotic relationship with our immune system. However, there are many species that are highly pathogenic.

These pathogenic species can cause harm to the tissues, thereby creating a serious inflammatory response that reverberates through many of the organs in the body. One alarming fact is the connection between these bacteria and cardiovascular disease. In fact, new research published by Dr. Bradley Bale, Dr. Amy Doneen and Dr. David Vigerust states that periodontal pathogens must be considered to be an independent, contributory cause of cardiovascular disease. Read the research. Watch our webinars.

How To Get Started

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The BiofilmDNA Test: The Most Advanced Measurement of Oral Pathogens

OraVital’s Biofilm Diagnostics Lab were the first to use Q-PCR (Quantitative Polymerase Chain Reaction) technology for identifying bacteria present in the oral cavity. The BiofilmDNA test is used to analyze planktonic and biofilm samples using saliva, subgingival, supragingival and tongue/throat samples.

Sample BiofilmDNA Test Report

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Q-PCR is a specific, sensitive, and quantitative method of accurately measuring the number of targeted species within an individual oral biofilm, as this method is able to detect even a single bacterial cell.

Q-PCR technology is used to analyze biofilm samples taken with OraVital’s flagship diagnostic tool, the BiofilmDNA test, which provides highly accurate DNA analysis of salivary, sub-gingival and tongue/throat samples taken via paper points and a wiping pad.

The BiofilmDNA Test: All Salivary DNA Tests Are NOT Created Equal!

Unlike swish and spit tests, OraVital’s BiofilmDNA Test provides a whole mouth picture of your patients’ oral health.  It is very important to test the throat and tongue because these reservoirs contribute to re-infections after gum care/implant placement. 

What’s more, this comprehensive test identifies the following 8 pathogens: 

• The Red Complex contains some of the most harmful opportunistic pathogens: Treponema denticola, Porphyromonas gingivalis and Tannerella forsythia.
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• Aggregatibacter actinomycetemcomitans aggressive bacteria that have been implicated in destructive periodontitis and causally for many systemic diseases such as CVD.
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• Two bacteria from the Orange Complex: Pepto streptococcus micros and Fusobacteria nucleatum, key components of pathogenic biofilm.
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• Streptococus mutans a species of bacteria that are responsible for the initiation of carious lesions
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• Candida albicans this fungus is frequently detected along with (heavy) periodontal infection with S. mutans in plaque biofilms and is also responsible for causing severe early childhood decay as well. It forms a reservoir in the oral cavity that leads to candidiasis and other lesions in the soft tissue which allows periodontal pathogens to easily enter the tissues through these wounds. This species is also detected at peri-implantitis sites co-colonized with other pathogens.